BeadChips & Bead Sets

Catalog IDs: GT-17-230

Developed through a collaboration between Illumina scientists and leading bovine thought leaders, the BovineHD BeadChip features more than 777,000 evenly spaced SNPs that provide comprehensive coverage of the bovine genome, enabling a diverse range of genetic research applications. This eight-sample BeadChip, along with the proven Infinium HD Assay, presents a powerful high-throughput solution for whole-genome studies in any breed of beef and dairy cattle.

Catalog IDs: WG-450-1002, WG-450-1003, WG-450-1004

The BovineLD BeadChip features 6,909 evenly spaced SNPs across the bovine genome, providing a robust imputation tool for characterizing genetic variation and accurately estimating genomic breeding value. This 24-sample BeadChip, along with the proven Infinium Assay, presents a powerful high-throughput solution for genomic selection in any breed of dairy and beef cattle.

Catalog IDs: WG-450-1007, WG-450-1008, WG-450-1009

The BovineSNP50 DNA Analysis BeadChip Kit contains 54,609 highly informative SNPs uniformly distributed across the entire genome of major cattle breed types. This empowers applications such as genome-wide enabled selection, identification of quantitative trait loci, evaluation of genetic merit of individuals, and comparative genetic studies.

Catalog IDs: WG-450-2001, WG-450-2002, WG-450-2003

Illumina's Cancer SNP Panel provides tools for conducting candidate-gene based association studies. The panel consists of 1,421 thoroughly screened and validated SNP loci from > 400 genes thought to be involved in cancer. Panel content was selected from the National Cancer Institute’s Cancer Genome Anatomy Project SNP500 Cancer Database.

Catalog IDs: GT-17-211

Featuring highly polymorphic SNP content and providing uniform genomic coverage, the CanineHD BeadChip enables the interrogation of genetic variation in any domestic dog breed. Importantly, this BeadChip presents an average of greater than 70 markers per megabase (Mb), providing ample SNP density for robust within-breed association and copy number variation (CNV) studies.

Catalog IDs: WG-440-1001, WG-440-1002, WG-440-1003

cDNA Synthesis Kits are used in the first step of the DASL Assay protocol where total RNA is converted to cDNA using both biotinylated nonamers (biotin-d(N)9) and biotinylated oligo d(T)18 that is then cleaned up and ready for use in the GoldenGate Assay amplification step.

Catalog IDs: DA-95-501, DA-95-502, DA-95-503

Illumina Custom GoldenGate Genotyping Panels allow researchers to create assays tailored directly to their specific needs for targeted region genotyping or fine-mapping of candidate disease association regions. GoldenGate Custom Panels provide flexibility and high data quality across a wide range of genomes and experimental designs.

Catalog IDs: GT-17-110

DNA Activation Kits are used in the first steps of the GoldenGate protocol to make biotin-labeled DNA that is then purified for use in the GoldenGate Assay amplification step. The DNA sample used in this assay is activated for binding to paramagnetic particles. This activation step requires a minimum input of DNA (250ng at 50ng/μl).

Catalog IDs: GT-95-201, GT-95-202

Illumina's DNA Test Panel is a SNP-based tool for pre-screening DNA samples for assay performance before conducting studies with larger numbers of loci. The Panel consists of 360 SNP loci distributed across the genome, chosen from the LinkageIVb Panel. DNA Test Panel loci were designed as genomic controls not likely to be associated with disease.

Catalog IDs: GT-17-222

Catalog IDs: WG-402-1001, WG-402-1002, WG-402-1003

GoldenGate Genotyping Kits provide reagents for the GoldenGate Genotyping Assay, including extension, ligation, cleanup, and hybridization to the multi-sample array format of choice. The kits are available with or without Uracil DNA Glycosylase. The Assay allows for a high degree of loci multiplexing during extension and amplification steps.

Catalog IDs: GT-95-203, GT-95-204, GT-95-205, GT-95-206, GT-201-1001, GT-201-1002, GT-201-1003, GT-201-1004, GT-201-1005

Catalog IDs: GT-222-1005

GoldenGate Indexing is a high-throughput genotyping solution that combines multi-sample indexing technology within the proven GoldenGate assay with automation control and positive sample tracking through an Illumina Laboratory Information Management System (LIMS). The GoldenGate Indexing assay is conveniently processed on the Universal-32 BeadChip.

Catalog IDs: GT-222-1003, GT-222-1004, GT-222-1005

Catalog IDs: GT-221-1116

GoldenGate Assays are deployed on the 12- or 32-sample Universal BeadChips during the GoldenGate Genotyping Assay hybridization step. Universal sequences hybridize to complementary sequences in the prepared sample. Both BeadChips make use of the high density self-assembly of oligonucleotide-coated beads.

Catalog IDs: GT-221-1003, GT-221-1004, GT-221-1005, GT-221-1008

Catalog IDs: GT-95-202, GT-201-1001, GT-201-1002, GT-201-1005, GT-201-1003

Catalog IDs: WG-311-1102, WG-311-1103, WG-311-1104, WG-311-1105

Catalog IDs: WG-311-1001, WG-311-1002, WG-311-1003, WG-311-1004

Catalog IDs: WG-311-1501, WG-311-1502, WG-311-1503, WG-311-1504

Catalog IDs: WG-310-1001, WG-310-1002, WG-310-1003, WG-310-1004

Catalog IDs: WG-311-1601, WG-311-1602, WG-311-1603

Catalog IDs: WG-31-151, WG-31-152, WG-31-153

Catalog IDs: WG-321-1003, WG-321-1004

The 12-sample HumanCytoSNP-12 BeadChip is a powerful, whole-genome scanning panel for efficient, high-throughput analysis of genetic and structural variations relevant to human disease. Many variations in the human genome that affect phenotypes can be detected including duplications, deletions, amplifications, copy-neutral LOH, and mosaicism.

Catalog IDs: WG-320-2101, WG-320-2102, WG-320-2103, WG-320-2104, WG-320-2105

Catalog IDs: WG-350-5501, WG-350-5502, WG-350-5503, WG-350-5504

The HumanHT-12 v4 Expression BeadChip content provides genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. HumanHT-12 delivers high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments.

Catalog IDs: BD-103-0204, BD-103-0604

The HumanLinkage V Panel Set is optimized to detect recombination events. Linkage analysis is a powerful approach for mapping the location of disease-causing loci. The likelihood of a recombination event occurring between two markers is related to the distance between them. Markers closest to a disease gene will co-segregate most strongly with the disease phenotype.

Catalog IDs: GT-17-240

Catalog IDs: WG-32-140, WG-32-141, WG-32-142

The completely redesigned four-sample HumanOmni1-Quad BeadChip contains aggressively selected SNPs and probes that capture more genomic variation and provide the best power for GWAS and CNV discovery. Cutting-edge content includes markers derived from the 1,000 Genomes Project, all three HapMap phases, and recently published studies.

Catalog IDs: WG-311-1110, WG-311-1111, WG-311-1112, WG-311-1113, WG-311-1123, WG-311-1124

Catalog IDs: WG-311-1123, WG-311-1124

The HumanOmni1S-8 (Omni1S) BeadChip is a remarkably priced tool for rapid integration of new rare 1000 Genomes content onto the Omni1/Express for 2-2.5M total variants (targeting MAF> 2.5%). Using the proven iScan or HiScanSQ System, this 8-sample BeadChip offers not only high throughput, but optimized tag SNP content from recently released 1000 Genomes Project pilot data. With the highest data quality and cutting edge content, including full support of copy number variation (CNV) applications, this powerful genotyping tool allows you to make more meaningful discoveries and publish faster.

Catalog IDs: WG-311-1114, WG-311-1115, WG-311-1116, WG-311-1117, WG-311-1129, WG-311-1130

Catalog IDs: WG-311-1129, WG-311-1130

The eight-sample HumanOmni2.5-8 BeadChip delivers comprehensive coverage of both common and rare SNP content from the 1000 Genomes Project (1kGP; MAF > 2.5%). It is designed to be maximally informative for diverse world populations.

Catalog IDs: WG-311-2514, WG-311-2513, WG-311-2512, WG-311-2511, WG-311-2521, WG-311-2523

Catalog IDs: WG-311-2521, WG-311-2523

The HumanOmni2.5-Quad (Omni2.5) BeadChip offers the most optimal and comprehensive set of both common and rare SNP content from the 1kGP (MAF>2.5%) for diverse world populations. Using the proven iScan or HiScanSQ System, this 8-sample BeadChip offers not only high throughput, but optimized tag SNP content from recently released 1000 Genomes Project pilot data. With the highest data quality and cutting edge content, including full support of copy number variation (CNV) applications, this powerful genotyping tool allows you to make more meaningful discoveries and publish faster.

Catalog IDs: WG-311-2514, WG-311-2513, WG-311-2512, WG-311-2511, WG-311-2521, WG-311-2523

Catalog IDs: WG-311-2521, WG-311-2523

The HumanOmni2.5S (Omni2.5S) BeadChip (Figure 1) provides over 2 million powerful markers selected from the 1000 Genomes Project (1kGP), targeting genetic variation down to 1% minor allele frequency (MAF). This content can be added to ongoing studies with Omni arrays for a total of up to 5 million markers per sample. The Omni2.5S can also be used as a standalone product to target the latest rare variants from the 1kGP. A semi-custom version of the BeadChip is also available, which can be tailored with up to 500K custom markers.

Catalog IDs: WG-311-2505, WG-311-2506, WG-311-2507, WG-311-2508, WG-311-2509, WG-311-2510, WG-311-2535, WG-311-2536

Catalog IDs: WG-311-2509, WG-311-2510, WG-311-2535, WG-311-2536

The HumanOmni5-Quad (Omni5) BeadChip delivers the most comprehensive coverage of the genome, leveraging powerful tag SNPs selected from the International HapMap and 1000 Genomes Projects that target genetic variation down to 1% minor allele frequency (MAF). Omni5 provides the flexibility to add up to 500K custom markers, allowing researchers to tailor the BeadChip for targeted applications and population-specific studies. Using the proven HiScan or iScan systems, along with the Infinium LCG Assay, this 4-sample BeadChip offers high-throughput sample processing, and optimized content for whole-genome genotyping and CNV applications.

Catalog IDs: WG-311-5001, WG-311-5002, WG-311-5003, WG-311-5004

Catalog IDs: SE-104-1005

Catalog IDs: WG-321-1005, WG-321-1006

Catalog IDs: WG-311-1701, WG-311-1702, WG-311-1703, WG-311-1704

Catalog IDs: BD-102-0203, BD-102-0603

Catalog IDs: BD-101-0203, BD-101-0603

Archival Formalin-Fixed Paraffin-Embedded (FFPE) samples hold an abundance of invaluable information for human cancer studies. Because these samples generally yield highly degraded DNA, they perform poorly in most whole-genome genotyping studies. The Infinium HD FFPE DNA Restore Kit can repair these degraded DNA samples in preparation for use with the Infinium HD Assay. After DNA extraction using one of many commercially available kits, the Infinium HD FFPE QC Kit is used to evaluate the quality of prospective DNA samples to determine if they are usable. The QC Kit provides primers and a DNA template for a real-time PCR assay that can be carried out using standard instrumentation and reagents purchased from an authorized vender. Extracted FFPE samples that pass the QC test are then eligible for restoration using the Infinium HD FFPE Restore Kit.

Catalog IDs: WG-321-1001, WG-321-1002, WG-321-1003, WG-321-1004, WG-321-1005, WG-321-1006, WG-314-1003, WG-314-1001, WB-314-1002

Illumina Human Exome BeadChips deliver unparalleled coverage of putative functional exonic variants selected from over 12,000 individual exome and whole-genome sequences. Markers were identified through a close collaboration with leading geneticists with the goal of developing an extensive catalog of exome variants. The exonic content consists of > 250,000 markers representing diverse populations—including European, African, Chinese, and Hispanic individuals—and a range of common conditions, such as type 2 diabetes, cancer, metabolic, and psychiatric disorders.

Catalog IDs: WG-353-1005, WG-353-1006, WG-353-1007

The Infinium HumanExome+ BeadChip provides unparalleled coverage of putative functional exonic variants selected from over 12,000 individual exome and whole-genome sequences. It delivers focused coverage of exonic regions, but does not include coverage outside of coding regions. Researchers can use this array to obtain new insights from previously genotyped cohorts, or run new studies focused on identifying functionally relevant associations. Researchers can include additional custom markers on the BeadChip to target specific regions of the genome with higher density, focus on populations of interest, or incorporate selected disease-related variants.

Catalog IDs: WG-353-1005, WG-353-1006, WG-353-1007, WG-353-1009

The Infiniuim HumanMethylation27 BeadChip is a solution for surveying genome-wide DNA methylation profiles. The BeadChip allows interrogation of 27,578 CpG highly informative sites per sample at single-nucleotide resolution. Using the Infinium Assay Illumina scientists created a panel of high-value methylation sites, including promoters and hotspots.

Catalog IDs: WG-311-2201, WG-311-2202

The Infinium HumanMethylation450 BeadChip's unique combination of comprehensive, expert-selected coverage, high sample throughput, and affordable price make it an ideal solution for epigenome-wide association studies (EWAS).

Catalog IDs: WG-314-1003, WG-314-1001, WG-314-1002

Catalog IDs: WG-314-1003, WG-314-1001, WG-314-1002

The Infinium HumanOmni5Exome BeadChip features > 250,000 exonic markers, along with > 4.3 million tag SNPs that span the human genome. This array delivers extensive coverage of common and rare variants (> 1% MAF) across the human genome, along with unprecedented coverage of coding variants within genes, providing the highest likelihood for obtaining new insight to potential disease pathways.

Catalog IDs: WG-311-5010, WG-311-5011, WG-311-5012, WG-311-5013

The Infinium HumanOmni5Exome+ BeadChip features > 250,000 exonic markers, along with > 4.3 million tag SNPs that span the entire human genome. This array delivers extensive coverage of common and rare variants (> 1% MAF) across the human genome, along with unprecedented coverage of coding variants within genes, providing the highest likelihood for obtaining new insight to potential disease pathways. Researchers can include additional custom markers on the BeadChip to target specific regions of the genome with higher density, focus on populations of interest, or incorporate selected disease-related variants.

Catalog IDs: WG-311-5014, WG-311-5015, WG-311-5016, WG-311-5017, WG-311-5018

The Infinium HumanOmniExpressExome BeadChip Kit delivers superior power for genome-wide association studies (GWAS), providing high sample throughput and comprehensive genomic content at the industry’s best price.

Catalog IDs: WG-350-2206, WG-350-2207, WG-350-2208, WG-350-2209

The Infinium HumanOmniExpressExome+ BeadChip maximizes coverage of coding variants within genes for genome-wide association studies (GWAS) focused on common variation. Researchers can include additional custom markers on the BeadChip to target specific regions of the genome with higher density, focus on populations of interest, or incorporate selected disease-related variants.

Catalog IDs: WG-353-2210, WG-353-2211, WG-353-2212, WG-353-2213, WG-353-1010

Catalog IDs: WG-400-1004

iSelect HD Custom Genotyping BeadChips offer access to the entire genome, and custom Infinium content, including non-human species. iSelect custom genotyping allows the design of a panel from 3,000-1,000,000 attempted bead types on a 24-sample (3,000 to 90,000), 12-sample (90,000 to 250,000) or 4-sample (250,000-1,000,000) BeadChip format. Assay virtually any genome marker, disease or pathway specific markers, rare variants, CNVs, and more.

Catalog IDs: WG-401-1004, WG-404-1004

The Maize SNP50 DNA Analysis Kit enables the interrogation of genetic variation across maize lines. Illumina has developed this BeadChip in collaboration with TraitGenetics, The French National Institute for Agricultural Research (INRA), and Syngenta. This BeadChip contains more than 50,000 validated markers derived from the B73 reference sequence. Importantly, this BeadChip presents an average of greater than 25 markers per megabase (Mb), providing ample SNP density for robust whole-genome genotyping studies.

Catalog IDs: WG-500-1001, WG-500-1002, WG-500-1003

The mouse has been increasingly recognized as an optimal genetic system for the study of the genetics of complex disease traits. The Mouse LD Linkage Panel is a SNP panel that offers a low-cost, efficient method for attaining genome-wide genetic data to identify quantitative trait loci, map candidate genes, and increase genotyping throughput.

Catalog IDs: GT-18-121

Illumina’s Mouse MD Linkage Panel consists of SNP loci that have been selected from the Wellcome-CTC Mouse Strain SNP Genotype Set. The Panel consists of 1,449 loci and is optimal for various mapping applications that include characterization of transgenic, congenic and knockout animals, and genetic mapping in advanced intercross mouse lines.

Catalog IDs: GT-18-131

Illumina’s MouseRef-8 v2.0 Expression BeadChips offer the most up-to-date content for mouse whole-genome expression profiling. Featuring content derived from the NCBI RefSeq database, these BeadChips reflect latest advancements in mouse genomics and provide the most biologically relevant information for murine genome studies.

Catalog IDs: BD-202-0202, BD-202-0602

Illumina’s MouseWG-6 v2.0 Expression BeadChips offer the most up-to-date content for mouse whole-genome expression profiling. Featuring content derived from the NCBI RefSeq database, these BeadChips reflect latest advancements in mouse genomics and provide the most biologically relevant information for murine genome studies.

Catalog IDs: BD-201-0202, BD-201-0602

The Multi_Format GEX Buffer Kit is for use with Expression BeadChips with low-volume seals. The kit includes sufficient hybridization buffer, wash buffer, and trays to process six BeadChips

Catalog IDs: BD-20-104

The OvineSNP50 BeadChip features over 54,241 evenly spaced probes that target SNPs. This BeadChip offers more than sufficient SNP density for genome-wide association studies and other applications such as genome-wide selection, determination of genetic merit, identification of quantitative trait loci, and comparative genetic studies.

Catalog IDs: WG-420-1001, WG-420-1002, WG-420-1003

The PorcineSNP60 DNA Analysis Kit features 62,163 evenly spaced probes offering more than sufficient SNP density for whole-genome association studies and other applications. This 12-sample BeadChip presents a superior solution for interrogating genetic variation in multiple porcine breeds, including Duroc, Landrace, Pietran, and Large White.

Catalog IDs: WG-410-1001, WG-410-1002, WG-410-1003

The RatRef-12 Expression BeadChip for genome-wide expression analysis contains 21,910 probes selected primarily from the NCBI RefSeq database (Release 16).

Catalog IDs: BD-27-303, BD-27-302

The VeraCode ADME Core Panel offers the most complete representation of clinically significant biomarkers, enabling researchers to concentrate on the ADME content that matters most.

Catalog IDs: VC-901-0200, VC-901-0201

VeraCode Carboxyl Bead Sets provide highly efficient tools for multiplexed protein-based assay development. Due to a carboxylated surface chemistry, VeraCode Carboxyl beads enable covalent attachment of proteins, peptides, nucleic acids, and other biomolecules. The 48 unique Carboxyl bead types can be pooled in varying combinations.

Catalog IDs: VC-920-8193, VC-920-8199, VC-920-8208, VC-920-8214, VC-920-8226, VC-920-8240, VC-920-8258, VC-920-8265, VC-920-8288, VC-920-8322

Catalog IDs: VC-201-2096, VC-201-2384

The VeraCode GoldenGate Genotyping Kits combine Illumina’s proven GoldenGate Genotyping Assay with the industry-leading data quality of the VeraCode technology to deliver an extremely robust system for high-throughput, custom 48-, 96-, 144-, 192-, and 384-plex SNP genotyping. These kits bundle DNA activation reagents, GoldenGate Assay reagents, a custom OPA, and VeraCode BeadPlates into one convenient kit.

Catalog IDs: VC-201-0048, VC-201-0096, VC-201-0144, VC-201-0192, VC-201-0384

Progression through the VeraCode GoldenGate Methylation Assay for focused DNA Methylation is aided by the VeraCode GoldenGate Methylation Analysis Kit, which includes DNA activation reagents, GoldenGate Methylation analysis reagents, a custom Oligo Pool for Methylation Analysis, and VeraCode BeadPlates.

Catalog IDs: VC-201-3096, VC-201-3384

True flexibility in the development of multiplex SNP genotyping assays can be achieved with Illumina VeraCode Uni­versal Capture Bead Sets. With highly stable, coded, bead sets that are precoupled with 23-mer capture oligonucleotides, researchers can develop their own multiplex assays, from single- to 144-plex, for their preferred assay methodology.

Catalog IDs: VC-910-0481, VC-910-0482, VC-910-5440, VC-910-5632, VC-910-5634, VC-910-5640, VC-910-5664, VC-910-5760, VC-910-6144, VC-910-6145, VC-910-6146, VC-910-6147, VC-910-6148, VC-910-6150, VC-910-6152, VC-910-6153, VC-910-6156, VC-910-6160, VC-910-6162, VC-910-6168, VC-910-6176, VC-910-6177, VC-910-6180, VC-910-6192, VC-910-6208, VC-910-6210, VC-910-6216, VC-910-6240, VC-910-6272, VC-910-6273, VC-910-6276, VC-910-6288, VC-910-6336, VC-910-6400, VC-910-6402, VC-910-6408, VC-910-6432, VC-910-6528, VC-910-6656, VC-910-6657, VC-910-6660, VC-910-6672, VC-910-6720, VC-910-6912, VC-910-7168, VC-910-7170, VC-910-7176, VC-910-7200, VC-910-7296, VC-910-7680

The Whole-Genome DASL HT Assay is the only integrated system optimized to produce genome-wide expression profiles from low-abundance or partially-degraded human RNA samples, especially those from formalin-fixed, paraffin-embedded (FFPE) tissues. It provides a high-multiplex, low-cost array solution from the simultaneous profiling of over 29,000 transcripts and is based on the HumanHT-12 v4 BeadChip.

Catalog IDs: DA-905-0024, DA-905-0096, DA-905-1024, DA-905-1096