Cycle Plot

The Data by Cycle plot displays plots that allow you to follow the progression of quality metrics during a run. These plots have the following features:

You can select the displayed metric, lane, surface, and base through the dropdown lists.
The plots are displayed with tailored scaling by default, or can be fixed by checking the Fix Scale checkbox.
The chevron in the top right hand corner toggles the plot between pane view and full screen view.
You can pan the graph by clicking-and-dragging, zoom in by using the mousewheel, and zooming in only on a particular axis by using the mouse wheel over that axis.
By right-clicking an image you can copy it to the clipboard.

Figure 3   Data by Cycle Plot

You can monitor the following quality metrics with this plot:

Intensity—This plot displays the intensity by color of the 90% percentile of the data for each cycle.
FWHM—The average full width of clusters at half maximum (in pixels). For a more detailed description, see http://en.wikipedia.org/wiki/Full_width_at_half_maximum.
Corrected Intensity—The intensity corrected for cross-talk between the bases and phasing and prephasing.
Called Intensity—The intensity for the called base.
% Base—The percentage of clusters for which the selected base has been called.
Signal to Noise—The signal to noise ratio is calculated as mean called intensity divided by standard deviation of non called intensities.
Error Rate—The calculated error rate, as determined by a spiked in PhiX control sample. If no PhiX control sample is run in the lane, this chart is not available.
% Perfect Reads—The percentage of reads that align perfectly, as determined by a spiked in PhiX control sample. If no PhiX control sample is run in the lane, this chart is not available.
%Q>20, %Q>30—The percentage of bases with a quality score of 20 or 30 or higher, respectively. These charts are generated after the 25th cycle, and the values represent the current cycle. A check box appears that lets you toggle between cumulative (include previous cycles) or not (just display current cycle).
Median Q-Score—The median Q-Score over all basesfor the current cycle. These charts are generated after the 25th cycle.

 

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Rev. August 20, 2012