Bowtie2

The MethylSeq workflow uses the Bowtie2 aligner. Bowtie2 aligns sequencing reads to long reference sequences, and supports gapped, local, and paired-end alignment modes.

For more information, see bowtie-bio.sourceforge.net/bowtie2/index.shtml.

1 Langmead B. and Salzberg S.L. (2012) Fast gapped-read alignment with Bowtie 2. Nature Methods, 9, 357–359.

 

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