Picard Metrics
Picard is a suite of tools in Java that work with next-generation sequencing data in BAM format. The app uses the CalculateHsMetrics tool in Picard to compute a set of Hybrid Selection specific metrics from an aligned SAM or BAM file. If a reference sequence is provided, AT/GC dropout metrics are calculated. GC and mean coverage information for every target can also be computed.
For more information, see broadinstitute.github.io/picard/