• All Files
Home/
Apply Variants Filters/Apply Filters/Association and Population Frequency Filters

Related articles

Association and Population Frequency Filters

Use the Association and Population Frequency Filters to filter data based on the allele frequency in population studies.

To set a variant filter for frequency values, enter a value from 0–1 in the field.

• Enter a value in the ALL field to filter by the average frequency across all options in a database.
• Use the Set all of the above option to quickly apply the same frequency value for all options in a database.

Filter

Description

Prediction

Filters data by showing the predicted pathogenicity for a disease.

ClinVar

Filters data by whether a variant corresponds to a variant reported in ClinVar.

• Allele-specific—The variant is associated with an allele.
• Position-specific—The variant is associated with a specific position independent of the allele.

Associations

Filters data by whether a variant corresponds to pathogenicity associations in MyKB or BSKN databases.

GnomAD Genomes

Filters data by allele frequency from the genomes data set of the Genome Aggregation Database (gnomAD) for all or specified populations.

GnomAD Exomes

Filters data by allele frequency from the exomes data set of the Genome Aggregation Database (gnomAD) for all or specified populations.

GnomAD Exomes replaces the ExaC filter.

TOPMed

Filters data by allele frequency from the Trans‑Omics for Precision Medicine database for all or specified populations.

1000 Genomes Project

Filters data by allele frequency from the 1000 Genomes Project for all or specified populations.

NHLBI Exome Sequencing Project

Filters data by allele frequency from the NHLBI exome sequencing project in global, European American, or African American populations.

Case Statistics

Filters data by allele frequency across local cases.

Global Minor Allele Population Frequency

Filters data by global minor allele frequency for the global population in dbSNP.

Population Frequency

Filters data to exclude any or all of the overlapping variants in the DGV or 1000 Genomes databases with a selected population frequency.