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The Illumina Experiment Manager software helps you create and edit well-formed sample sheets for Illumina sequencers and analysis software.
Illumina recommends using the Experiment Manager before starting sample or library preparation. The Experiment Manager can detect and warn of sub-optimal index combinations. By creating the sample sheet prior to sample or library preparation, you can try a different index combination without risking your samples.
You can use the Illumina Experiment Manager to create sample sheets for any Illumina sequencer and for any Nextera or TruSeq libraries.