Add Predictive Association Details

1. Add one or more diseases or phenotypes as follows.
  1. In the Disease/Phenotype field, enter a disease or phenotype.
    As you type, a list of possible matches appears to assist your search. The name of the ontology is displayed in parentheses after the phenotype name.
  2. Select an entry from the list or press Enter to accept the first match.
  3. To remove an entry, select ×.
2. Select the Direction drop-down arrow, and then select the direction.
3. Add one or more drugs tested as follows.
  1. In the Drugs Tested field, enter a drug name.
    As you type, a list of possible matches appears to assist your search.
  2. Select an entry from the list or press Enter to accept the first match.
  3. To remove an entry, select ×.
4. Select the Validation Level drop-down arrow, and then select the level of validation. See View Variant Details for a description of Validation levels and their order of significance.

NOTE

Report the highest level of validation from all supporting evidence.

5. Select the Mechanism drop-down arrow, and then select the mechanism.
6. Select the Confidence drop-down arrow, and then select the level of confidence.
7. [Optional] Enter a brief description in the Curator Summary field.
8. Add at least one evidence. See Adding Evidence.
9. Select Save.

The association is submitted for approval and is listed with a status of In Progress.