Add Drug Label Evidence

Use Drug Label evidence to support Predictive associations.

1. In the Evidence panel, select the Add New Evidence drop-down arrow, and then select Drug Label.
2. Enter the drug brand in the Brand field.
3. Enter the drug uses in the Uses field.
4. Select the Authorizing Authority drop-down arrow, and then select one of the following options:
FDA—Food and Drug Administration
EMA—European Medicines Agency
HCSC—Health Canada (Santé Canada)
PMDA—Pharmaceutical and Medical Devices Agency
5. [Optional] Enter the following information about the drug:
Enter the therapeutic area in the Therapeutic Area field.
Enter the purpose in the Purpose field.
Enter the active ingredient in the Active Ingredient field.
Enter the biomarker in the Biomarker field.
6. Select the Support Type drop-down arrow, and select a support type. The list of support types varies based on the association type.
7. Select the Evidence Strength drop-down arrow, and then select an evidence strength. Refer to ACMG Standards and Guidelines for classification criteria.

NOTE

ACMG Supporting strength is equivalent to BaseSpace Variant Interpreter Weak strength.

8. [Optional] Enter a summary of the evidence in the Evidence Summary field.
9. Select Save Evidence.