TopHat

TopHat is a fast splice junction mapper for RNA-seq reads that can only be used with Bowtie or Bowtie2. TopHat uses Bowtie or Bowtie2 to map RNA-seq reads, and then it analyzes the mapping results to identify splice junctions between exons.

For more information, see http://ccb.jhu.edu/software/tophat/index.shtml.