Isaac Aligner
The Isaac Aligneraligns DNA sequencing data, single or paired-end, with read lengths 32–150 bp and low error rates using the following steps:
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Candidate mapping positions—Identifies the complete set of relevant candidate mapping positions using a 32-mer seed-based search. |
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Mapping selection—Selects the best mapping among all candidates. |
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Alignment score—Determines alignment scores for the selected candidates based on a Bayesian model. |
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Alignment output—Generates final output in a sorted duplicate-marked BAM file, and summary file. |
Enrichment v3.0 Online Help
For Research Use Only. Not for use in diagnostic procedures.