Introduction

Introduction

The Tumor Normal v2.0 v2.0 App detects somatic variants from a matched pair of tumor and normal samples. The Isaac Genome Alignment Software aligns both tumor and normal samples to a reference. The Isaac Variant Caller calls germline small variants, structural variants, and copy number abnormalities (CNAs). Also, Strelka calls somatic small variants in the tumor matched samples, structural variants, and somatic copy number variants (CNVs).