Universal Copy Service Vulnerability

Thank you for visiting the customer support site for the UCS vulnerability.

The following table lists the impacted instruments and software versions. All instruments require actions outlined in the instruction guide. Illumina recommends that you read the instructions before downloading any software.

NOTE: For any software versions not specified in the table, your instrument is not impacted by this vulnerability and no actions are required. Please return the verification form attached to your notification confirming the action was not performed. 

Instrument Impacted Software Versions Actions Required
iScan iScan Control Software 4.0.0

Configure UCS account credentials.

NOTE: The instructions indicate that iScan Control Software v4.0.0 and above require a software update. Version 4.0.0 does not need a software update and only requires configuration of UCS account credentials.
iScan Control Software 4.0.5 Contact Illumina Technical Support to upgrade to v4.2.1.
iSeq 100 All Configure UCS account credentials.
MiniSeq MiniSeq Control Software 2.0 and newer Configure UCS account credentials.
MiSeq MiSeq Control Software 4.0 and newer Update software per the actions for this instrument listed here.
MiSeqDx MiSeq Control Software 4.0 (RUO Mode)

Update software per the actions for this instrument listed here.
MiSeqDx Operating Software 4.0.1 and newer

Update software per the actions for this instrument listed here.
NextSeq 500/550 NextSeq Control Software 4.0 Update software per the actions for this instrument listed here.
NextSeq Control Software 4.1 Update software per the actions for this instrument listed here.
NextSeq 550Dx NextSeq Control Software 4.0 (RUO Mode) Update software per the actions for this instrument listed here.
NextSeq Control Software 4.1 Update software per the actions for this instrument listed here.
NextSeq Operating Software 1.0.0-1.3.1 Update software per the actions for this instrument listed here.
NextSeq Operating Software 1.3.3 and newer Update software per the actions for this instrument listed here.
NextSeq 1000/2000 NextSeq Control Software 1.4.1

Update the system software with NextSeq 1000/2000 Control Software Suite v1.5.0 Installer.
NovaSeq 6000 NovaSeq Control Software 1.7 and older

Configure UCS account credentials.

NOTE: The instructions state that the firewall port must be closed for these software versions. Closing the firewall port is not required.
NovaSeq Control Software 1.8
  1. Update system software with NovaSeq Software Suite Installer v1.8.1.59.
  2. Configure UCS account credentials.
  3. Close firewall port.

The following video is meant to provide additional context to the UCS Instruction Guide. Please read the instructions first.

This video:

  • is specifically for Windows 10 instruments (this excludes NovaSeq 6000 RUO).
  • demonstrates how to modify the user configuration of the UCS service to "Local Service" (standard user).

NOTE: This video is applicable only to instruments where UCS is currently configured to use "Local System". If UCS is not configured to use "Local System" on your instrument, refer to the Instruction Guide for additional details.

LINK to demonstration video.

UCS Instructions

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