TruSight Oncology 500 Documentation

DRAGEN TruSight Oncology 500 Analysis Software Documentation

All versions support TSO 500 v1 assay; versions 2.6.2 and above support TSO 500 v2 assay.

DRAGEN TSO 500 Release Supported Assays User Guides Release Notes Date Posted
v2.6
  • TSO 500
  • TSO 500 HT
  • TSO 500 HRD
  • TSO 500 v2 (v2.6.2 only)
  • Jul 30, 2025
  • Jun 25, 2025
  • Jan 16, 2025
  • Oct 25, 2024

v2.5

 

  • TSO 500
  • TSO 500 HT
  • TSO 500 HRD
  • Jun 25, 2025
  • Dec 16, 2024
  • Mar 27, 2024
  • Nov 8, 2023
  • Nov 8, 2023
v2.1
  • TSO 500
  • TSO 500 HT
  • TSO 500 HRD
  • Jul 25, 2023
  • Feb 17, 2023
  • Mar 2, 2023
v1.1
  • TSO 500
  • TSO 500 HT
  • Aug 29, 2022
  • Apr 28, 2022

TruSight Oncology 500 Analysis Software Documentation

All versions support TSO 500 v1 assay; versions 2.0 and above support TSO 500 v2 assay.

TSO 500 Release Supported Assays User Guides Release Notes Date Posted
v2.4
  • TSO 500
  • TSO 500 HT
  • Dec 17, 2024

v2.3

 

  • TSO 500
  • TSO 500 HT
  • Jun 25, 2025
v2.2
  • TSO 500
  • TSO 500 HT
  • Dec 17, 2024
  • Feb 8, 2021
  • Nov 13, 2020
v2.1
  • TSO 500
  • Sep 11, 2020
v2.0
  • TSO 500
  • Sep 11, 2020
  • Sep 11, 2020
v1
  • TSO 500 (DNA only)
  • Jan 8, 2019

Product Literature

TYPE

SIZE

DATE

Sarcoma Fusions 101 Flyer
Download
Application note < 1 MB Feb 27, 2020
TruSight Oncology 500 v2
Download
Data sheet 2 MB
Enzymatic fragmentation as an alternative to ultrasonic shearing in the TruSight Oncology 500 v2 DNA workflow
Download
Technical note 10 MB
Use of an alternative MIDI plate in the TruSight Oncology 500 workflow
Download
Technical note 11 MB
Automating the TruSight Oncology 500 v2 assay with the Hamilton Microlab NGS STAR MOA platform
Download
Technical note 9 MB
Automating the TruSight Oncology 500 v2 assay with the Beckman Coulter Biomek i7 workstation
Download
Technical note 10 MB
Use of cfDNA as input for TruSight Oncology 500 v2
Download
Technical note < 1 MB
Automating the TruSight Oncology 500 v2 workflow with the Hamilton NGS STARlet liquid handler
Download
Technical note 10 MB Jun 24, 2026
TruSight Oncology 500 and TruSight Oncology 500 High-Throughput
Download
Data sheet 1 MB Jul 16, 2020
Input Recommendations for TMB, MSI, and Small Variant Analysis with TruSight Oncology 500
Download
Technical note
Analysis of TMB and MSI Status with TruSight Oncology 500
Download
Application note