Add Family Members for Trio Analysis
Add the analysis results of parents and siblings to a proband case to provide additional data for family-based filtering.
| 1. | Import an analysis result for the proband and each family member. |
You can import the files individually or in a batch with a manifest that contains metadata for all files in the batch. For information about importing VCF files, see Import Variant Call Files.
| 2. | Open each case and edit the metadata as needed. |
| • | The Sample Class in each case must be set to Germline. |
| • | The Sex of each subject must be set to Male or Female. |
| • | An optional Family ID can be added to each case. |
| 3. | From the proband case, enter the subject ID of each family member and set their affection status. |
After saving changes, an associated analysis for each family member is added to the proband case.