Downloads

The downloads listed on this page are only compatible with Local Run Manager 2.x. MiniSeq customers who are not running AmpliSeq for Illumina panels should visit the Local Run Manager for MiniSeq downloads page instead.

Downloads

Description
 
File Info
Date Posted
Local Run Manager Off-Instrument v2.0 Installer and Release Notes

This download contains the Local Run Manager Off-Instrument v2.0 installer and release notes.

Local Run Manager RNA Amplicon Analysis Module

This download contains the installer for the Local Run Manager RNA Amplicon Analysis Module.

Local Run Manager DNA Amplicon Analysis Module

This download contains the installer for the Local Run Manager DNA Amplicon Analysis Module.

The DNA Amplicon v2.1 module requires the updated hg19 annotation database to complete analysis. Download the hg19 Annotation Database update file or the latest hg19 genome build and see README: Installing the hg19 Reference Genome Nirvana Annotation Database.

GRCh38Decoy genome is supported for DNA Amplicon Analysis Module v2.1. Download the GRCh38Decoy Annotation Database update file and see README: Installing the GRCh38Decoy Reference Genome Nirvana Annotation Database.

If you are using the DNA Amplicon v1.0 module, continue to use the previous hg19 build. For the DNA Amplicon v1.0 installer, contact Illumina Technical Support.

Illumina Annotation Engine Support File for TruSight Tumor 15

The Illumina Annotation Engine Support files enable analysis of the TruSight Tumor 15 workflow. This download includes a link to the installer from a secure file transfer location.

Local Run Manager Generate FASTQ Analysis Module

This download contains the installer for the Local Run Manager Generate FASTQ Analysis Module.

Local Run Manager DNA Enrichment Analysis Module

This download contains the installer for the Local Run Manager DNA Enrichment Analysis Module.

Local Run Manager TruSight Tumor 15 Analysis Module

Designed for libraries prepared with the TruSight Tumor 15 kit, the TruSight Tumor 15 analysis module aligns reads specified in the manifest file, and then reports somatic variants of a set of reference panel genes associated with cancer.

Local Run Manager Amplicon DS Analysis Module

This download contains the installer for the Local Run Manager Amplicon DS Analysis Module.

The Amplicon DS Analysis Module v2.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager Resequencing Analysis Module

This download contains the installer for the Local Run Manager Resequencing Analysis Module.

The Resequencing Analysis Module v2.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager Small RNA Analysis Module

This download contains the installer for the Local Run Manager Small RNA Analysis Module.

The Small RNA Analysis Module v2.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager RNA Fusion Analysis Module

This download contains the installer for the Local Run Manager RNA Fusion Analysis Module. This module is designed specifically for RNA libraries prepared with the TruSight RNA Fusion Panel kit.

The RNA Fusion Analysis Module v2.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Due to resource limitations, the iSeq 100 system prevents the installation of the RNA Fusion Module for on-instrument analysis. Illumina recommends using the Off-Instrument version of Local Run Manager on a more powerful system to enable analysis.

Local Run Manager PCR Amplicon Analysis Module

This download contains the installer for the Local Run Manager PCR Amplicon Analysis Module.

The PCR Amplicon Analysis Module v1.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager 16S Metagenomics Analysis Module

This download contains the installer for the Local Run Manager 16S Metagenomics Analysis Module.

The 16S Metagenomics Analysis Module v1.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager Assembly Analysis Module

This download contains the installer for the Local Run Manager Assembly Analysis Module.

The Assembly Analysis Module v1.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Local Run Manager Library QC Analysis Module

This download contains the installer for the Local Run Manager Library QC Analysis Module.

The Library QC Analysis Module v1.0 requires Local Run Manager Framework v2.0.0 or higher and is not compatible with Local Run Manager Framework v1.3.1 or lower.

Reference Genome and Annotation Files

 

Human Reference Genome (hg19) and Annotation Files

This download contains the hg19 human reference genome, as well as annotation files used by the Illumina Annotation Engine.

 

Templates

Description
 
File Info
Date Posted
Local Run Manager v2.0 Custom Library Prep Kit Template

This template provides guidance for adding custom library prep kit definitions to Local Run Manager v2.0.

Library Prep Kit Definition Files

Description
 
File Info
Date Posted
Nextera DNA Flex Library Prep Kit Files

This download contains the library prep kit definition files required to use the Nextera Flex library prep kit in Local Run Manager.