New Methods for Old Problems: Using Immunogenomics to Decode the Anti-Tumor T-Cell Repertoire

Cancer arises due to an accumulation of genetic alterations, which can lead to the production of mutant proteins not expressed in normal cells, allowing recognition by the immune system. Kellie Smith, PhD, Assistant Professor of Oncology at Johns Hopkins University School of Medicine, presents her research on understanding the interplay of cancer neoantigens with the immune response at Illumina Exhibitor Spotlight Theater presentation at AACR 2019.