TruSight Oncology 500 Portfolio

TruSight Oncology 500 Assay

Now with HRD* *Not available in Japan

Study relevant DNA and RNA cancer biomarkers from FFPE tumor tissue, now including HRD through an accessory kit to assess the Genomic Instability Score (GIS).

TruSight Oncology 500 High-Throughput Assay

Batch up to 192 samples at a time while using the same panel content and tissue input type as the TruSight Oncology 500 assay.

TruSight Oncology 500 ctDNA Assay

Study liquid biopsies (blood) to assess circulating tumor DNA (ctDNA) with similar DNA panel content as the TruSight Oncology 500 assay.

*:연구 전용이며, 본 사양은 임상/진단 용도로 승인되지 않음.

Pan-Cancer Biomarkers

Detection of currently relevant DNA & RNA variants for multiple types of cancer.
Some key biomarkers include:
Pan-Cancer Biomarkers      NTRK1        NTRK2        NTRK3        MSI        TMB
Lung Melanoma Colon Ovarian Breast Gastric Bladder Sarcoma
AKT1 BRAF AKT1 BRAF AKT1 BRAF MSH5 ALK
ALK CTNNB1 BRAF BRCA1 AR KIT PMS2 APC
BRAF GNA11 HRAS BRCA2 BRCA1 KRAS TSC1 BRAF
DDR2 GNAQ KRAS FOXL2 BRCA2 MET   CDK4
EGFR KIT MET HRD ERBB2 MLH1   CTNNB1
ERBB2 MAP2K1 MLH1 KRAS FGFR1 PDGFRA   ETV6
FGFR1 NF1 MSH2 PDGFRA FGFR2 TP53   EWSR1
FGFR3 NRAS MSH6 TP53 HRD     FOXO1
KRAS PDGFRA NRAS   PIK3CA     GLI1
MAP2K1 PIK3CA PIK3CA   PTEN     KJT
MET PTEN PMS2         MDM2
NRAS TP53 PTEN         MYOD1
PIK3CA   SMAD4         NAB2
PTEN   TP53         NF1
RET             PAX3
TP53             PAX7
              PDGFRA
              PDGFRB
              SDHB
              SDHC
              SMARCB1
              TFE3
              WT1

The genes and biomarkers listed in this table are a subset of all genes included in the panel. To see the full gene list, view the product datasheet, available under Product Literature on the respective product pages.

Illumina NGS Methods Guide

Analytical Evaluation & Verification Service

The TruSight Oncology 500 Analytical Evaluation Service facilitates alignment with the latest CAP, AMP, and European standards. Use the service to evaluate analytical performance characteristics and integrate products into your workflows while reducing overall evaluation time by ~60%.

View Service

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